The obesity epidemic that is prevailing in most countries of the world is generally attributed to the increased amount of opportunities to be in positive energy balance in a context of modernity. This obviously refers not only to sedentariness and unhealthy eating that may dominate life habits of many individuals but also to unsuspected non-caloric factors which produce discrete allostatic changes in the body. In this paper, the focus is put on the impact of some of these factors with the preoccupation to document the allostatic burden of weight loss.
Epidemiological studies emphasize the possible role of persistent organic pollutants (POPs) in obesity and the metabolic syndrome. These pollutants are stored in adipose tissue (AT). The aim of the paper was to study the effects of POPs on human adipose cells and rodent AT.
Replacement of caloric beverages with noncaloric beverages may be a simple strategy for promoting modest weight reduction; however, the effectiveness of this strategy is not known. The authors compared the replacement of caloric beverages with water or diet beverages (DBs) as a method of weight loss over 6 mo in adults and attention controls (ACs).