The World Health Organisation (WHO) and experts have recommended aminosidine as a first -line drug in the treatment of kala-azar, in place of Sodium Stibo Gluconate. This is after Aminosidine was tried by top kala-azar expert, Dr T K Jha, and his co-workers at kala-azar Research Centre, Muzaffarpur. The trial were conducted in collaboraiton with the UNDP, the World Health Organisation (WHO), and the the World Bank (WB), Bihar still has more than 1 lakh kala-azar patients, of which about 40,000 were resistant cases.