Acute encephalitis syndrome in children in Muzaffarpur: hypothesis of toxic origin

One among three long-standing mystery diseases listed in Wikipedia is acute encephalitis syndrome (AES) in Muzaffarpur, Bihar. This disease has remained for over two decades without determining a cause for; hence it is called mystery disease. It occurs annual seasonal outbreaks during the months of April-July, affecting hundreds of children with 40-60% mortality, according to local physicians.

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