World malaria report 2023

India topped countries in the South-East Asia region for the most number of malaria cases and deaths in 2022, according to this report published by the World Health Organization (WHO). Each year, WHO’s World malaria report provides a comprehensive and up-to-date assessment of trends in malaria control and elimination across …

Zimbabwe: Malaria Claims 5 in Beitbridge

Beitbridge — Five people in Beitbridge District have died following an outbreak of a strain of falciparum malaria, while over 800 cases have tested positive, it has emerged. The disease, which at the onset of the rainy season was concentrated on the eastern parts of the district, has spread rapidly …

Malaria drug for pregnant women also combats sexually transmitted infections - research

A drug given to pregnant women to combat malaria also offers protection against sexually transmitted infections (STIs), and boosting doses of the 'double protection' treatment cuts the risk of infant deaths, researchers said on Thursday. Giving pregnant women regular doses of antimalarial drugs greatly reduces the danger of life-threatening birth …

Net loss? Agrochemicals and insecticide resistance in the fight against malaria

In Africa, a combination of better medicines and the widespread use of insecticides to kill mosquitoes has led to the decline in malaria cases and deaths. Millions of people in places like Dano are living longer, healthier lives because of this public health campaign. They are also more prosperous when …

Study: Better Housing a Powerful Tool for Malaria Prevention

Improving housing conditions may provide a boost to malaria prevention at a time when other efforts may be losing steam, according to new research. As Africa rapidly moves away from traditional mud-and-thatch housing, experts see a chance for architects and urban planners to join the fight against the disease. Bed …

Malaria goes sub-microscopic, proves its existence in Chennai

CHENNAI: Even as the State health department is confidently striding ahead to get Chennai declared as malaria-free by the World Health Organisation, a study done by the National Institute of Malaria Research (NCMR), Chennai along with other institutions has shown the existence of asymptomatic malaria which remains undetected. This sub-microscopic …

Quantification of labile heme in live malaria parasites using a genetically encoded biosensor

Malaria parasites degrade substantial quantities of hemoglobin to release heme within a specialized digestive vacuole. Most of this heme is sequestered in an inert crystal. However, the concentration of bioavailable, labile heme in the parasite’s cytosol was unknown. We developed a biosensor to provide the first quantitative insights into labile …

Housing improvements and malaria risk in sub-Saharan Africa: A multi-country analysis of survey data

Improvements to housing may contribute to malaria control and elimination by reducing house entry by malaria vectors and thus exposure to biting. We tested the hypothesis that the odds of malaria infection are lower in modern, improved housing compared to traditional housing in sub-Saharan Africa (SSA). Original Source

Anti-malarial, antibiotics cost rises by 150%

The Pharmaceutical Society of Nigeria (PSN) has warned that the prices of essential medicines in the country, such as anti-malarial drugs and antibiotics have risen by over 150 per cent in less than two years. According to the PSN, the implementation of a 20 per cent duty on imported medicines …

Experimental vaccine protects against multiple malaria strains

An experimental malaria vaccine protected healthy subjects from infection with a malaria strain different from that contained in the vaccine, according to a study published today in the Proceedings of the National Academy of Sciences (PNAS). The research was conducted by scientists at the University of Maryland School of Medicine …

Funds for research on neglected diseases lowest in 2015

Global funding for research and development on neglected diseases reached a historic low in 2015, driven by declining public sector investment. The G-FINDER report by Australia-based independent group, Policy Cures Research, says that the decline is due to the lack of funding by rich countries. According to it, this is …

'Malaria vaccine tests have been successful'

The development provides hope in the fight against the deadly disease which has continued to threaten the lives of pregnant women and children. The news came as a report published in the Lancet Infectious Diseases this week showed that the Sanaria's Pf- SPZ vaccine confers significant protection against natural Malaria …

Experimental Vaccines Offer Promise in War on Malaria

Two vaccine candidates have been shown to be effective — in one case, 100 percent effective — in preventing malaria. The biotech firm Sanaria Inc. of Rockville, Maryland, developed the vaccines. They prime the immune system against the malaria parasite by introducing live but weakened sporozoites — the earliest spore …

Neglected disease research and development: a pivotal moment for global health

The ninth G-FINDER survey reports on 2015 global investment into research and development (R&D;) of new products for neglected diseases, and identifies trends and patterns across the nine years of global G-FINDER data. In all, 185 organisations completed the survey for FY2015, which covered: 39 neglected diseases; 160 product areas …

Humanitarian leaders discuss Sustainable Development Goals in Africa

More than 300 high-profile representatives from NGOs, businesses, government and UN organisations are set to convene at the Aid & Development Africa Summit in Nairobi this February exchanging innovative and sustainable solutions for improving aid delivery and development strategy in sub-Saharan East Africa. Delivering Sustainable Development Goals (SDGs) requires a …

SC83288 is a clinical development candidate for the treatment of severe malaria

Severe malaria is a life-threatening complication of an infection with the protozoan parasite Plasmodium falciparum, which requires immediate treatment. Safety and efficacy concerns with currently used drugs accentuate the need for new chemotherapeutic options against severe malaria. Here we describe a medicinal chemistry program starting from amicarbalide that led to …

New initiative forged to eliminate malaria in Zambia

A new partnership to support the Zambian government’s ambitious campaign to eliminate malaria by 2020 has been announced. The initiative is spearheaded by the EXASOL, a high-performance in-memory analytic database developer, and PATH, an international nonprofit organization and global leader in health and innovation. “Data analytics is often discussed as …

Malaria superbugs spreading fast in Asia

Multidrug-resistant malaria superbugs have taken hold in parts of Thailand, Laos and Cambodia, threatening to undermine progress against the disease, scientists said. They also warned of further spread of these parasites through India to Africa. The superbugs can beat off the best current treatments, artemisinin and piperaquine. “The emergence and …

Andhra Pradesh: Rise in mosquito numbers rings alarm bells

Unhygienic conditions coupled with fluctuations in temperature are major reasons for the unusual breeding of mosquitoes. NIZAMABAD: Mosquito breeding has increased at an alarming rate in the rural and urban areas in Nizamabad and Kamareddy districts, leading to more cases of vector-borne diseases in the area. In the normal course, …

Malaria drugs fail for first time on patients in UK

The patients had caught malaria when visiting Africa. A key malaria treatment has failed for the first time in patients being treated in the UK, doctors say. The drug combination was unable to cure four patients, who had all visited Africa, in early signs the parasite is evolving resistance. A …

Eight African countries honoured for effective fight against malaria

Ethiopia, Swaziland, Uganda, Botswana, Cabo Verde, Comoros, DRC and Chad have been honoured for their significant progress in the fight against malaria. The eight countries were awarded on Monday by the African Leaders Malaria Alliance (ALMA) at the 28th African Union Summit in Addis Ababa, Ethiopia. ALMA is an alliance …

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